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Optimisation of cardiac resynchronisation therapy: addressing the problem of “non-responders”
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  • Published on:
    The rate of non-response to CRT is substantially underestimated

    Dear Editor,

    Fox et al. raise the important issue of non-response to CRT and suggest the rate of non-response to CRT is 25%, a figure which is widely quoted. However a careful examination of the published data suggests that this is a substantial underestimate of the problem.

    The non-responder rates in the studies using subjective or (relatively) objective functional capacity as the main definition of respon...

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    Conflict of Interest:
    None declared.
  • Published on:
    Positive QRS in aVR & aVL - is it an indicator for non-responders?
    • Nikola Gjorgov, Head, Dept. of Cardiac Electrophysiology
    • Other Contributors:
      • Ivan Trajkov, Dejan Kovacevic, Vladimir Boskov

    In discussion and exchange of ideas with colleagues (Europace, 2005) there is a consensus among some of us performing CRT that a positive QRS deflection in lead aVR and aVL is somewhat an indicator for "non- responders" when that patient is implanted with an biventricular pacing device.

    This observation needs to be further scrutinized and varified by both a prospective studies as well as with retrospective analys...

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    Conflict of Interest:
    None declared.