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- DM, diabetes mellitus
- IDDM, insulin dependent diabetes mellitus
- NIDDM, non-insulin dependent diabetes mellitus
- PCI, percutaneous coronary intervention
- STEMI, ST segment elevation myocardial infarction
Patients with acute ST segment elevation myocardial infarction (STEMI) with diabetes mellitus (DM) have an increased mortality and morbidity when compared with patients without DM.1 Information is limited about clinical outcome of with STEMI and DM treated with reperfusion. Furthermore, patients with DM have a higher rate of thrombolysis failure.2,3 Information is also limited on long term outcome of patients with DM treated with primary percutaneous coronary intervention (PCI),4 which is the reperfusion treatment of choice.5
We therefore studied one year mortality among patients with and without DM in a large cohort of patients with acute STEMI treated with primary PCI. Furthermore, we studied the impact of preadmission treatment for DM, either oral medication or with insulin.
Between January 1997 and December 2002, 1463 consecutive and unselected patients were admitted to our hospital with acute STEMI. Of the 1463 patients, 17 were lost to follow up and for another 138 patients data about DM status was not available. The remaining 1308 patients constituted the study cohort. Follow up information was obtained one year after the initial event by written questionnaire sent to all patients. If necessary outpatients’ reports were reviewed and general practitioners were contacted by telephone. Baseline clinical and angiographic data were collected prospectively on a …