Article Text
Abstract
Objective: To investigate the effect of reducing stent length on the rate of target lesion restenosis.
Design: In a prospective investigation, acute and long term results of a short stenting procedure were analysed by quantitative angiography and compared with results of a conventional stenting procedure selected according to a matched pairs analysis.
Patients: Short stents were implanted in 400 consecutive patients with 464 lesions and conventional stents in 430 patients. Demographic and lesion characteristics were comparable between groups.
Interventions: In short stenting, the shortest stent length to cover only segments with > 30% reduction in vessel diameter was used. In conventional stenting, full coverage of a stenotic vessel segment was intended.
Main outcome measures: The mean stent lengths of the short stent group (9.8 (4) mm) and the conventional stent group (16.3 (7) mm) differed significantly (p < 0.0001); all other procedural and angiographic parameters were the same. Procedural success was similar for both groups. Control angiography after six months was conducted in 92% of patients.
Results: Short stenting resulted in both less restenosis (68 of 431 (15.8%)) than conventional stenting (93 of 381 (24.4%), p = 0.007) and less late lumen loss (0.6 (0.6) mm v 0.75 (0.5) mm, p = 0.0001). Residual stenosis (< 45%) in adjacent vessel segments after short stenting did not affect the restenosis rate. Only the implantation of a ⩽ 9 mm stent predicted the absence of restenosis in a multivariate analysis.
Conclusion: Shortening the length of bare metal stents reduces the restenosis rate as compared with conventional stenting.
- DES, drug eluting stents
- MACE, major adverse cardiac events
- PTCA, percutaneous transluminal coronary angioplasty
- TVR, target vessel revascularisation
- stent
- balloon dilatation
- restenosis
Statistics from Altmetric.com
Footnotes
-
Published Online First 9 May 2005