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Plasma C reactive protein concentration indicates a direct relation between systemic inflammation and social deprivation

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  • D O’R conceived of measuring C reactive protein (CRP) in both studies, wrote the first and final versions of the paper, and is the guarantor. D O’R, M N U, G C M W, and C J P conceived of the idea of analysing the relation between CRP and deprivation. G C M W conceived of the Midspan family study, M N U was the principal investigator, and A M performed the statistical analysis for Midspan. C J P was Study Director for WOSCOPS, M C coordinated CRP analysis, and M R and J N performed the statistical analysis for WOSCOPS.

  • C reactive protein analyses were funded by British Heart Foundation grant PG/97160

  • Conflict of interest: None

  • Ethics: Both the WOSCOPS and Midspan family study were approved by local research ethics committees

    Independence of researchers: This research was carried out and the manuscript was written independently and without input or influence from the funder.