A 48-year-old man had been treated with amiodarone doses of 200–400 mg daily for 3 years (total dose of 330 g). He noted the gradual development of marked facial discolouration (panel A) and believed that he had suffered from this stigmatising effect as much as from the underlying heart disease. Amiodarone treatment was discontinued, and he subsequently underwent successful “photothermolytic” treatment using …