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Clinical trials of endothelin antagonists in heart failure: publication is good for the public health


The failure of endothelin antagonists to show benefit in heart failure cannot be understood until all the clinical trials are fully published

  • CHF, chronic heart failure
  • EARTH, Endothelin A Receptor Antagonist Trial in Heart Failure
  • HEAT, Haemodynamic and Neurohumoral Effects of Selective Endothelin A Receptor Blockade in Chronic Heart Failure
  • NYHA, New York Heart Association

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