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The autoantibody rheumatoid factor may be an independent risk factor for ischaemic heart disease in men
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Other responses

  • Published on:
    Rheumatoid factor and heart disease: supporting evidence regarding increased risk of mortality
    • Craig J Currie, Department of Medicine
    • Other Contributors:
      • Pete Conway and Chris D Poole

    Dear Editor,

    A recent study in Heart by Edwards and colleagues found an interesting association between rheumatoid factor (RF) and ischaemic heart disease [1]. We examined independently the related issue of the role of systemic inflammation in relation to clinical outcome in a forthcoming study [2]. This subsequent study reports an association between systemic inflammation, as measured by C-reactive protein (CRP...

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    Conflict of Interest:
    None declared.
  • Published on:
    Rheumatoid Factor-? Is it a biomarker of inflammation or an independent risk factor for IHD

    Dear Editor,

    I read with interest the original article by Christopher J Edwards et al about the possibility of Rheumatoid factor being an independent risk factor for Ischaemic Heart Disease (1).The contribution of inflammation to the initiation and progression of coronary atherosclerosis is well established.I agree this study adds support to the importance of inflammation in atherosclerosis. The concept of autoimmunit...

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    Conflict of Interest:
    None declared.