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The author’s reply:
  1. Christopher J Edwards
  1. Dr C J Edwards, Department of Rheumatology, Southampton General Hospital, Southampton SO16 6YD, UK; cedwards{at}

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We read with interest the comments from Dr Currie and colleagues.

It is encouraging that their group has demonstrated that rheumatoid factor (RF) is an independent risk factor for mortality in a large cohort of patients from South Wales, supporting the importance of RF as a biomarker for poor prognosis in a number of clinical situations. Our work has shown a strong association between the presence of RF and ischaemic heart disease in men from a general …

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