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Acute coronary syndromes
Postprocedural single-lead ST-segment deviation and long-term mortality in patients with ST-segment elevation myocardial infarction treated by primary angioplasty
  1. G De Luca1,
  2. H Suryapranata2,
  3. J P Ottervanger2,
  4. J C A Hoorntje2,
  5. A T M Gosselink2,
  6. J-H Dambrink2,
  7. M-J de Boer2,
  8. A W J van’t Hof2
  1. 1
    Division of Cardiology, Ospedale “Maggiore della Caritè”, Universitè del Piemonte Orientale “A Avogadro”, Novara, Italy
  2. 2
    Department of Cardiology, ISALA Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
  1. Dr A W J van’t Hof, ISALA Klinieken, Hospital De Weezenlanden, Department of Cardiology, Groot Wezenland 20, 8011 JW Zwolle, The Netherlands; v.r.c.derks{at}


Objective: To evaluate the prognostic role of postprocedural single-lead residual ST-segment deviation for electrocardiographic evaluation of myocardial perfusion in patients with ST-segment elevation myocardial infarction (STEMI) treated by primary angioplasty.

Design: Prospective observational clinical cohort study.

Setting: Tertiary referral centre.

Patients: 1660 patients treated with primary angioplasty for STEMI.

Main outcome measure: Mortality at 1-year follow-up.

Results: Single-lead ST-segment deviation significantly correlated with infarct size, predischarge ejection fraction, distal embolisation and myocardial blush grade 3. At 1-year follow-up, 63 patients had died. The method correlated well with 1-year mortality. At multivariate analysis, after correction for baseline demographic, clinical and angiographic variables, postprocedural single-lead ST-segment deviation showed better accuracy than residual single-lead ST-segment elevation or resolution and residual 12-lead ST-segment deviation.

Conclusions: This study showed that maximal residual ST-segment deviation in a single lead at 3 hours after the procedure is an easy and accurate predictor of 1-year mortality after primary angioplasty for STEMI.

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  • Competing interests: None declared.

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