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  • Beneficial effects of aggressive low-density lipoprotein cholesterol lowering in women with stable coronary heart disease in the Treating to New Targets (TNT) study

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Coronary artery disease
Beneficial effects of aggressive low-density lipoprotein cholesterol lowering in women with stable coronary heart disease in the Treating to New Targets (TNT) study
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  • Published on: 23 November 2015
    High-dose statin therapy, women and cancer
    • Mark R. Goldstein, MD, MD
    • Other Contributors:
      • Luca Mascitelli, MD; Medical Service, Comando Brigata alpina "Julia", Udine, Italy; Francesca Pezzetta, MD; Cardiology Service, Ospedale di Tolmezzo, Tolmezzo, Italy

    Dear Editor,

    We read the interesting secondary analysis of the 4.9-year Treating to New Targets (TNT) study [1] reporting on the effects of aggressive low- density lipoprotein (LDL) cholesterol lowering in women (median age of 63.5 years) with stable coronary heart disease. Based on the reported data, we have serious concerns regarding the large excess in cancer mortality seen among the women randomized to high-d...

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    Conflict of Interest:
    None declared.