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The authors’ reply:
  1. M M Winter1,2,
  2. B J Bouma1,
  3. B J M Mulder1,3
  1. 1
    Department of Cardiology, Academic Medical Centre, Amsterdam. The Netherlands
  2. 2
    Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands
  3. 3
    Department of Cardiology, University Medical Centre Utrecht, Utrecht, The Netherlands
  1. Correspondence to Professor B J M Mulder, Academic Medical Centre, Department of Cardiology, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; b.j.mulder{at}

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We thank Dr Szymañski for his critical review1 of our paper on the therapeutic options for patients with a systemic right ventricle.2 We agree with the author that studies on the effect of angiotensin converting enzyme (ACE) inhibitors, and angiotensin II receptor (AT-II) antagonists are hampered by the heterogeneity of the patient population, and that strict definition of the study population is of …

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