Article Text

Download PDFPDF
Interventional cardiology
Radial artery anomaly and its influence on transradial coronary procedural outcome
  1. T S Lo1,
  2. J Nolan1,
  3. E Fountzopoulos1,
  4. M Behan2,
  5. R Butler1,
  6. S L Hetherington3,
  7. K Vijayalakshmi3,
  8. R Rajagopal4,
  9. D Fraser4,
  10. A Zaman3,
  11. D Hildick-Smith2
  1. 1
    Department of Cardiology, University Hospital of North Staffordshire, Stoke-on-Trent, UK
  2. 2
    Department of Cardiology, Brighton and Sussex University Hospital, Brighton, UK
  3. 3
    Department of Cardiology, Freeman Hospital and Newcastle University, Newcastle-upon-Tyne, UK
  4. 4
    Department of Cardiology, Manchester Heart Centre, Manchester, UK
  1. Dr T S Lo, Department of Cardiology, University Hospital of North Staffordshire, Newcastle Road, Stoke-on-Trent ST4 6QG, UK; tsnlo{at}


Background: The transradial approach for percutaneous coronary procedures has the advantage of reduced access site complications but is associated with specific technical challenges in comparison with the transfemoral approach. Transradial procedure failures can sometimes be due to variation in radial artery anatomy. However, data describing such variations are limited.

Objective: To evaluate the incidence and impact of radial artery anomalies in patients undergoing transradial coronary procedures.

Methods: Retrograde radial arteriography was performed in all patients presenting for a first-time radial procedure. Patient characteristics, radial artery anatomy and procedural outcome were assessed.

Results: 1540 consecutive patients were studied, 70.6% male, mean (SD) age 63.6 (11.1) years. The overall incidence of radial artery anomaly was 13.8% (n = 212). 108 (7.0%) patients had a high-bifurcating radial origin, 35 (2.3%) had a full radial loop, 30 (2.0%) had extreme radial artery tortuosity and 39 (2.5%) had miscellaneous anomalies such as radial atherosclerosis and accessory branches. Overall transradial procedural success was 96.8%. Procedural failure was more common in patients with anomalous anatomy than in patients with normal anatomy (14.2% vs 0.9%, p<0.001). Procedural failure in patients with high radial bifurcation, radial loop, severe radial tortuosity and other anomalies was 4.6%, 37.1%, 23.3% and 12.9%, respectively. 15 (1%) vascular complications occurred, all of which were treated conservatively without ischaemic sequelae.

Conclusion: Anomalous radial artery anatomy is relatively common and is a significant cause of procedural failure. Within each specific anomalous pattern there is a differential procedural failure rate. This has implications for clinical practice and suggests a need for imaging of the radial artery after sheath insertion.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Competing interests: None.