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NICE, drug-eluting stents and the limits of trial data
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To the editor: Dr de Belder asks the question how to determine the worth of drug-eluting stents?1 The answer to this question does not lie in the trial data. The function of trial data is to establish the extent of clinical-effectiveness to a given degree of certainty. In this context, while a trend may generate a hypothesis it does not establish clinical-effectiveness.
There is no balance between clinical- …
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