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Mitral regurgitation in patients with aortic stenosis undergoing valve replacement
  1. P Unger1,
  2. C Dedobbeleer1,
  3. G Van Camp2,
  4. D Plein3,
  5. B Cosyns4,
  6. P Lancellotti5
  1. 1
    Department of Cardiology, ULB-Erasme Hospital, Brussels, Belgium
  2. 2
    Department of Cardiology, Universitair Ziekenhuis-UZ Brussel, Brussels, Belgium
  3. 3
    Department of Cardiology, Clinique Saint-Jean, Brussels, Belgium
  4. 4
    Department of Cardiology, CHIREC-Hôpital de Braine-l’Alleud, Belgium
  5. 5
    Department of Cardiology, Centre Hospitalier Universitaire Sart Tilman, Liège, Belgium
  1. Correspondence to Professor Philippe Unger, Cardiology Department, ULB-Erasme Hospital, 808 route de Lennik, B-1070 Brussels, Belgium; philippe.unger{at}


Mitral regurgitation is a frequent finding in patients with aortic stenosis scheduled for aortic valve replacement. Detection of mitral regurgitation in such patients has important implications, as it can independently affect functional status and prognosis. When mitral regurgitation is moderate to severe, a decision to operate on both valves should only be made following a careful clinical and echocardiographic assessment. Indeed, double-valve surgery increases perioperative and postoperative risks, and mitral regurgitation may improve spontaneously after isolated aortic valve replacement. Better understanding of the determinants of these changes appears particularly crucial in the light of recent advances in percutaneous aortic valve replacement.

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  • Funding PU has received a grant from the Fonds pour la Chirurgie Cardiaque; CD has received a grant from the Fonds Erasme.

  • Competing interests None.

  • Provenance and Peer review Not commissioned; externally peer reviewed.