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  • Periprocedural myocardial injury during elective percutaneous coronary intervention: is it important and how can it be prevented?

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Periprocedural myocardial injury during elective percutaneous coronary intervention: is it important and how can it be prevented?
  1. F Cuculi,
  2. C C S Lim,
  3. A P Banning
  1. Department of Cardiology, Oxford Radcliffe Hospitals, Oxford, UK
  1. Correspondence to Dr Adrian P Banning, The John Radcliffe, Headley Way, Oxford OX3 9DU, UK; adrian.banning{at}orh.nhs.uk

Abstract

Periprocedural myocardial injury (PMI) is common after percutaneous coronary intervention (PCI). Periprocedural infarction (myocardial infarction type 4a) occurs after at least 10% of PCI procedures and has an impact on long-term prognosis. Measurement of biomarkers to allow assessment of PMI is an important tool for clinical and research purposes and should be routine after every PCI (troponin I or T and CK-MB). The importance of oral and intravenous antiplatelet agents and other drugs which have been proven to reduce PMI is discussed.

  • PTCA–troponin–statins
  • HMG CoA–clopidogrel–platelet aggregation inhibitors
  • coronary angioplasty
  • coronary stenting
  • microvascular
  • preconditioning
  • anticoagulation

https://doi.org/10.1136/hrt.2009.186189

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    Footnotes

    • Funding APB is partially funded by the NIHR Biomedical Research Centre Oxford.

    • Competing interests None.

    • Provenance and peer review Not commissioned; externally peer reviewed.