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Periprocedural myocardial injury during elective percutaneous coronary intervention: is it important and how can it be prevented?


Periprocedural myocardial injury (PMI) is common after percutaneous coronary intervention (PCI). Periprocedural infarction (myocardial infarction type 4a) occurs after at least 10% of PCI procedures and has an impact on long-term prognosis. Measurement of biomarkers to allow assessment of PMI is an important tool for clinical and research purposes and should be routine after every PCI (troponin I or T and CK-MB). The importance of oral and intravenous antiplatelet agents and other drugs which have been proven to reduce PMI is discussed.

  • PTCA–troponin–statins
  • HMG CoA–clopidogrel–platelet aggregation inhibitors
  • coronary angioplasty
  • coronary stenting
  • microvascular
  • preconditioning
  • anticoagulation

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