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Translational medicine
Cardiac stem cell therapy: progress from the bench to bedside
  1. Matthew J Lovell,
  2. Anthony Mathur
  1. Department of Cardiology, London Chest Hospital, Queen Mary University of London, Barts and the London NHS Trust, London, UK
  1. Correspondence to Professor Anthony Mathur, Department of Cardiology, London Chest Hospital, Queen Mary University of London, Barts and the London NHS Trust, Bonner Road, London E2 9JX, UK; a.mathur{at}qmul.ac.uk

Abstract

In the rush to assess the role of stem cell therapy for cardiovascular disease the details of translation are easily overlooked. This review summarises the progress to date in translating the exciting preclinical results of cardiac repair into man and considers the questions that this area of research has stimulated about the challenges of moving from bench to bedside.

  • Stem cell
  • cardiac
  • regenerative medicine
  • clinical trials

https://doi.org/10.1136/hrt.2009.192385

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    Footnotes

    • Funding This work forms part of the research themes contributing to the translational research portfolio of Barts and the London Cardiovascular Biomedical Research Unit, which is supported and funded by the National Institute of Health Research. Dr Matthew Lovell was funded by the British Heart Foundation during work included in this manuscript. Professor Mathur's clinical research in this area is funded by the Heart Cells Foundation, UK Stem Cell Foundation and Barts and the London Charity.

    • Competing interests None.

    • Provenance and peer review Commissioned; externally peer reviewed.