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Aspirin and coronary artery disease
  1. Erik Lerkevang Grove1,
  2. Morten Würtz1,
  3. Gunnar Hilmar Gislason2,
  4. Steen Dalby Kristensen1,
  5. Anne-Mette Hvas3
  1. 1Department of Cardiology, Aarhus University Hospital, Skejby, Denmark
  2. 2Copenhagen University Hospital Gentofte, Hellerup, Denmark
  3. 3Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark
  1. Correspondence to Dr Erik Lerkevang Grove, Department of Cardiology, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, Aarhus DK-8200, Denmark; erikgrove{at}dadlnet.dk

https://doi.org/10.1136/hrt.2010.201145

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    The Authors' reply: We appreciate the letter by Tormen et al1 in response to our paper.2 Atherosclerosis is a multifactorial, slowly progressing vascular disease involving the retention of cholesterol-containing lipoproteins and the generation of proinflammatory molecules that recruit macrophages and ultimately results in thickening of the vascular wall. However, thrombosis is mainly caused by platelet-dependent thrombus formation on pre-existing atherosclerotic plaques.3 Acknowledging that aspirin has anti-inflammatory activity, …

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    Footnotes

    • Linked articles 201137.

    • Competing interests None.

    • Ethics approval This study was conducted with the approval of the Central Denmark Region Committees on Biomedical Research Ethics.

    • Provenance and peer review Commissioned; not externally peer reviewed.

    Linked Articles

    • PostScript
      Aspirin and coronary artery disease
      Eduardo M da Rosa William C Tormen Edna F Lopes
      Heart 2010; 96 1684-1684 Published Online First: 23 Aug 2010. doi: 10.1136/hrt.2010.201137