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Epidemiology
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Family history of premature coronary heart disease and risk prediction in the EPIC-Norfolk prospective population study
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  • Published on: 23 November 2015
    Family history of premature coronary heart disease and risk prediction
    • M. Adnan Nadir, Research Fellow and Cardiology Registrar
    • Other Contributors:
      • Allan D Struthers

    We read the article by Sivapalaratnam and colleagues with great interest. Although, self-reported family history of coronary heart disease (CHD) was an independent risk factor for future CHD events in this study, the addition of family history of CHD to Framingham Risk Score (FRS) failed to improve the overall risk prediction of future CHD events. Since age is a heavily weighted risk factor incorporated in the contempora...

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    Conflict of Interest:
    None declared.