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Clinical and research medicine: Cardiovascular clinical pharmaceutical research
e0347 The changes of heart rate turbulence (HRT) in sleep apnoea-hypopnoea syndrome (SAHS)
  1. Tong Guangming,
  2. Tong Guangming
  1. Department of Cardiology The Second Hospital Affiliated To Soochow University


Objective We investigated the changes of heart rate turbulence (HRT) in sleep apnoea- hypopnoea syndrome (SAHS).

Methods 75 patients underwent overnight polysomnography for clinically suspected SAHS and simultaneous Holter monitoring (23:00–6:00), According to the apnoea-hypopnoea index (AHI), the patients were assigned to group SAHS (+) (AHI ≥5, n=52) or group SAHS (-) (AHI <5, n=23). HRT (onset, slope) of two groups were compared.

Results Turbulence slope (TS) of group SAHS (+) was significantly lower in group SAHS (-) (p<0.01), turbulence onset of two groups all smaller than zero, turbulence onset of group SAHS (+) were higher than group SAHS (-)’s, but no significant difference, the number of ventricular premature contractions of group SAHS (+) were more than group SAHS (-)’s, but also no significant difference.

Conclusions Heart rate turbulence phenomenon diminishes in sleep apnoea- hypopnoea syndrome patients, indicating demages in cardiac autonomic activity in SAHS, turbulence slope decreasing could be considered as prognosis index of SAHS.

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