Objective To study the relationship between ankle-brachial index (ABI) and the severity of coronary artery stenosis.

Method This study enrolled 180 patients, who underwent coronary angiography and ABI measurement in addition to date collection regarding cardiovascular risk factors. They were divided into two groups according to ABI. The correlation between cardiovascular risk factors, ABI and the CAD severity were analysed.

Results Gensini score (69.0±20.1), three vessel (56, 56%) and B₂/C type stenotic lesion (79, 79%) was significantly higher in ABI<0.9 group compared with control group (50.7±17.6), (19, 23.8%), (31, 38.8%).

Result Gensini score (69.0±20.1), three vessel (56, 56%) and B₂/C type stenotic lesion (79, 79%) was significantly higher in ABI<0.9 group, Compared with control group (50.7±17.6), (19, 23.8%), (31, 38.8%). Binary regression analysis showed that ABI, correlated with several risk factors, was a statistically significant independent predictor for three vessel or complex (B₂/C) stenotic lesions and odds ratio were 3.620 and 4.011 respectively. The stepwise multivariable regression analysis shown, ABI<0.9 (R=−3.018, P<0.05) and age (R=1.206, P<0.05) enter the gensini score regression equation.

Conclusion ABI is negatively correlated with the degree of coronary artery stenosis. ABI≤0.9 is a good predictor of severe coronary artery disease.