Objective To study the characteristics of coronary artery lesion between Uygur and Han nationality type 2 diabetic patients with coronary heart disease.

Methods 648 patients were analysed retrospectively in our hospital. The coronary artery lesion was evaluated by the number, location and Gensini scores.

Results Compared with the Han patients, mean age in the Uygur patients was lower in same Gensini scores group (p<0.05). Along with the age increasing, Gensini scores increased gradually. Gensini scores of Uygur patients were significantly higher than those of Han patients in same age groups. The prevalence of three-vessel lesion was the highest in both Han (46.9%) and Uygur patients (45.9%). Severity of coronary artery disease increased with age, the prevalence of single-vessel lesion gradually reduced and the prevalence of three- vessel lesion gradually increased.

Conclusions Severity of coronary artery disease increased with age. Severity of coronary artery lesion in Uygur patients is significantly more serious than in Han patients at the same age. Compared with Han patients, the age of onset of similar degree coronary atherosclerosis in the Uygur patients is younger.