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Propafenone contraindicated in the elderly?
  1. Charles J H J Kirchhof1,
  2. H J G M Crijns2,
  3. I C van Gelder2
  1. 1Department of Cardiology, Rijnland Hospital, Leiderdorp, The Netherlands
  2. 2Academic Hospital Maastricht, Maastricht, The Netherlands
  1. Correspondence to Charles JHJ Kirchhof, Department of Cardiology, Rijnland Hospital, Leiderdorp, The Netherlands; ch.kirchhof{at}

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To the Editor With great interest we read the paper by Alboni et al.1 The investigators studied intravenous class Ic antiarrhythmic drug (AAD) administration (propafenone and flecainide) as a predictor for adverse effects when used in a ‘pill-in-the-pocket’ regimen (PITP).

Alboni and colleagues suggest that intravenous administration of flecainide or propafenone for pharmacological conversion of atrial fibrillation to sinus rhythm cannot predict the occurrence of adverse effects when these agents are subsequently …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; not externally peer reviewed.

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