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To the Editor With great interest we read the paper by Alboni et al.1 The investigators studied intravenous class Ic antiarrhythmic drug (AAD) administration (propafenone and flecainide) as a predictor for adverse effects when used in a ‘pill-in-the-pocket’ regimen (PITP).
Alboni and colleagues suggest that intravenous administration of flecainide or propafenone for pharmacological conversion of atrial fibrillation to sinus rhythm cannot predict the occurrence of adverse effects when these agents are subsequently …
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