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Heart-type fatty acid-binding protein in the early diagnosis of acute myocardial infarction: a systematic review and meta-analysis
  1. James A Shand,
  2. David J McEneaney,
  3. Ian B Menown
  1. Craigavon Area Hospital, Portadown, Northern Ireland, UK
  1. Correspondence to Dr James A Shand, Craigavon Area Hospital, 68 Lurgan Road, Portadown, Northern Ireland, UK; james.shand{at}

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To the Editor We read with interest the systematic review and meta-analysis by Bruins Slot et al concerning early diagnosis of myocardial infarction (MI) using heart-type fatty acid-binding protein (H-FABP).1 We agree with their summary that when used in isolation, H-FABP may not offer a diagnostic advantage over the current troponin standard. However, it should be noted that in five of the included studies constituting 1573 patients (42% of the pooled cohort), no …

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  • Linked article 223412.

  • Competing interests J A Shand receives partial salary support as a research fellow from Randox Laboratories, Crumlin, Northern Ireland.

  • Provenance and peer review Not commissioned; not externally peer reviewed.

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    Madeleine Bruins Slot Frans Rutten Hans Reitsma Geert van der Heijden Arno W Hoes