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The Authors' reply We thank Shand et al for their comments1 on our systematic review and meta-analysis.2
We agree with Shand et al that when assessing the diagnostic value of heart-type fatty acid-binding protein (H-FABP), it should be measured in the relevant time interval (ie, 1–24 h after the onset of complaints). Because H-FABP is a sensitive early marker of myocardial necrosis, it can have major advantages over troponin within the first 6 h after symptom onset, when troponin can still be …
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