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To the Editor The study performed by Breet et al1 supported our previous suggestion that a cut-off of >550 aspirin reaction units (ARU) was too high to identify high on-treatment platelet reactivity (HPR).2 The cut-off defined by the highest quartile (461 ARU) from our study2 is remarkably similar to the 454 ARU cut-off value associated with 1-year outcomes in the Breet et al study.1 Moreover, across ARU quartiles, reactivity to ADP and collagen …
Funding This study was partly supported by grants from the Institute of the Health Sciences, Gyeongsang National University and Sinai Hospital Baltimore.
Competing interests Dr Jeong received honoraria from Sanofi-Aventis, Daiichi Sankyo Inc. and Otsuka. Dr Gurbel received research grants, honoraria and consultant fees from Haemoscope, AstraZeneca, Schering-Plough/Merck, Medtronic, Lilly/Daiichi Sankyo Inc., Sanofi-Aventis/Bristol Myers, Portola, Boston Scientific, Bayer, Novartis, Accumetrics, Boehringer Ingelheim and Johnson & Johnson.
Patient consent Obtained.
Ethics approval Ethics approval was obtained from the Gyeongsang National University Hospital institutional review board.
Provenance and peer review Commissioned; internally peer reviewed.