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Coronary artery disease
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Arterial stiffness is increased in families with premature coronary artery disease
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  • Published on: 23 November 2015
    Considering a possible application to prevent or to treat arterial stiffness

    I was impressed to read the results of Mulders et al. (1), who provided evidence that first-degree relatives of patients with premature coronary artery disease had increased arterial stiffness (measured by pulse-wave velocity) in the absence of coronary artery disease. The authors also found a relation between arterial stiffness and coronary artery calcification.

    As a physician, I wonder about ways to prevent the devel...

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    Conflict of Interest:
    None declared.
  • Published on: 23 November 2015
    It is usually the cigarettes that did it

    It should be remembered that in INTERHEART, nine risk factors accounted for 90% of the population attributable risk of a myocardial infarction in men and 94% in women - these did not include family history.[1] Thus, on a population basis, I would disagree with the authors that 'A positive family history of premature coronary artery disease (CAD) is an important risk factor for cardiovascular disease (CVD)'. It is however...

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    Conflict of Interest:
    None declared.