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Considering a possible application to prevent or to treat arterial stiffness
  1. Rainer Spiegel
  1. Correspondence to Dr Rainer Spiegel, Internal Medicine Unit, Klinik Adelheid, Hoehenweg 71, Unteraegeri CH-6314, Switzerland; Rainer.Spiegel{at}

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To the Editor I was impressed at reading the results of Mulders et al,1 who provided evidence that first-degree relatives of patients with premature coronary artery disease had increased arterial stiffness (measured by pulse-wave velocity) in the absence of coronary artery disease. The authors also found a relation between arterial stiffness and coronary artery calcification.

As a physician, I wonder about ways to prevent the development of coronary artery disease in these individuals who seem to have this disposition. I found it interesting that patients with …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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