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Caffeine does not increase the risk of atrial fibrillation: a systematic review and meta-analysis of observational studies
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  • Published on:
    Reply to comment "Dose-response relationship between caffeine and risk of atrial fibrillation"

    We thank Yan Qu and colleagues for their interest in our publication.1 In our systematic review we concluded that caffeine exposure was not associated with increased AF risk. We also have performed a qualitative evaluation of dose-response, which uses the relative proportions of caffeine exposure within each study and the risk of atrial fibrillation (AF). Pooling the relative risk (RR) of low caffeine intake from each st...

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    Conflict of Interest:
    None declared.
  • Published on:
    Dose-response relationship between caffeine and risk of atrial fibrillation
    • Yan Qu, Doctor
    • Other Contributors:
      • Dan Hu, Junqian Huang, Yuchun Wang, Wenjie Jiang, Dongfeng Zhang

    Dear Editor, We read with great interest the recent meta-analysis showing that low-dose caffeine may have a protective effect on risk of atrial fibrillation, while no favorable effect was found for high dose of caffeine, and a sketch of a J-shape curve was speculated on the association of caffeine with risk of atrial fibrillation.1 Therefore, to clarify the dose-response relationship on caffeine and risk of atrial fibrilla...

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    Conflict of Interest:
    None declared.