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- patent forame ovale
- percutaneous closure
- brain ischemic lesions
- magnetic resonance imaging
- cryptogenic stroke
To the Editor The recently published meta-analysis by Wolfrum et al assessed the ability of percutaneous closure of patent foramen ovale (PFO) to reduce the incidence of recurrent stroke based on three randomised controlled clinical trials (RCT). This analysis did not demonstrate a superiority of the closure of PFO …
Contributors EA, GC and PGC wrote the manuscript.
Competing interests None.
Provenance and peer review Not commissioned; internally peer reviewed.