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The findings of Grandi et al1 provide valuable evidence that calcium is associated with all-cause mortality in patients with coronary heart disease. Historically, the role of calcium in healthy ageing has been equivocal. For example, Mursu et al2 found an inverse relationship with calcium and mortality. In response to this finding, it was speculated that calcium's beneficial effect may stem from a reduced ability to synthesise calciol from 7-dehydrocholesterol in the skin as we age.3
Given the present report by Grandi …
Contributors All authors made significant contributions to the design, implementation, analysis and interpretation of the study.
Competing interests None.
Patient consent Obtained.
Ethics approval University of Newcastle and Northern Sydney Central Coast Health.
Provenance and peer review Not commissioned; internally peer reviewed.
Data sharing statement This article is not an original research article, it is intended for the correspondence section of Heart. Unpublished data from the study alluded to in the letter is available to workers listed on ethics committee approval(s) as appropriate and as determined by A/Profs Lucock and Veysey, the lead scientist and clinician, respectively. All data is stored password protected.