Article Text

ASSA13-10-22 Research on Blood Pressure Circadian Rythm of Chronic Kidney Disease Patients
  1. Liu Xing1,1,
  2. Yuan Hong1,
  3. Huang Wei2
  1. 1Clinical Pharmacology Center, The Third Xiangya Hospital of Central South University
  2. 2Department of Cardiology, The Third Xiangya Hospital of Central South University


Objective To investigate the characteristic of blood pressre and its circadian rhythm in chronic kidney disease patients.

Methods Clinical data of patients who underwent 24h ambulatory blood pressure monitoring from 2011 to 2012 in Department of Nephrology of the Third Hospital of Xiangya were collected and analysed.

Results In the 139 CKD with hypertensive patients; there were 87.1% non-dippers and reverse dippers. With the decline of creatinine clearance compared with mild CKD patients, the rate of nocturnal blood pressure fall in moderate to severe CKD patients was more significant (P < 0.001). Even in CKD with normal blood pressre patients, the blood pressure circadian rythm was mainly non-dippers (P = 0.008).

Conclusions The blood pressre rythm disorders are very common in CKD patients.

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