Objectives To study the effects of supplementing Qi and activating blood circulation herbs on lung protection in acute lung injury (ALI) ventilation patients.

Methods 82 cases of ALI patients were enrolled and randomly divided into two groups. Routine treatment was for 42 cases of control group while treatment with adding supplementing Qi and activating blood circulation herbs for 40 cases of treatment group, by 10 ml per time for 14 consecutive days with each day three times; Compared hemodynamics, changes of arterial blood gas, assay of pdymorphonuclears (PMN) value and the image of bronchoscopes between two groups in T₁, T₃, T₇ and T_14.

Results PMN, MAP, HR, SVR, PaO₂ and PH of treatment group were significantly improved than control group during T₁, T₃, T₇ and T₁₄ (P<0.05), especially in PMN (P<0.01). The compared difference was remarkable on hemodynamics, changes of arterial blood gas, assay of PMN value between treatment group and control group. The image of bronchoscopes in treatment group was improved significantly.

Conclusions The intervention of supplementing Qi and activating blood circulation herbs can effectively protect the lung function from ALI patients who received ventilation.