Background Data comparing survival outcomes for women vs men transported for pPCI absent.
Objectives To asses the impact of gender on 30-day mortality of patients with STEMI transported for pPCI.
Methods. The data from the PRAGUE-1 and PRAGUE-2 trials were analyzed. Studies compared thrombolysis in the community hospital and pPCI after transport to cardiocentre. We analysed a group of 520 patients treated with thrombolysis and 530 transported to pPCI.
Results Women were older, with a higher risk profile. They had longer ischemia time. Mortality of patients treated with TL was significantly higher in women compared to men (15% vs. 9%, p=0,043). There was no significant gender difference in mortality in the PCI group (8,2% of women vs. 6,2% of men, p=0,409). Mortality of women treated with on-site TL was nearly twice as high as mortality of women transported for pPCI (p=0,043). After adjustment in a multivariate model the odds ratio for mortality in females was 0.74 (95% CI. 0.26-2.05; P=0,556)
Conclusion Long distance transport of women with STEMI from a community hospital to a tertiary PCI centre is a significantly more effective treatment strategy than on-site TL. Gender did not determine survival in patients transported for pPCI.
- myocardial infarction
- transport for percutaneous coronary intervention
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