Article Text

other Versions

Download PDFPDF
Personalised external aortic root support
  1. Tom Treasure1,
  2. J JM Takkenberg2,
  3. John Pepper3
  1. 1Clinical Operational Research Unit, Department of Mathematics, University College London, London, UK
  2. 2Department of CardioThoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
  3. 3Department of Cardiac Surgery, Royal Brompton Hospital, London, UK
  1. Correspondence to Professor Tom Treasure, Clinical Operational Research Unit, Department of Mathematics, University College London, London WC1H 0BT, UK; tom.treasure{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Dear Editor, Valve replacing and valve-sparing root replacement were devised on the operating table and evolved by trial and error. Different times set different standards. By contrast, after 4 years of research collaboration between surgeons, anatomists and engineers (2000–2004), personalised external aortic root support (PEARS) has followed a standard protocol in 42 patients with over 170 patient-years of intention-to-treat analysis, and has been systematically and rigorously evaluated.

Cameron’s ‘two technical points’1 do not accurately reflect how this operation is in fact performed.2 The proximal …

View Full Text


  • Competing interests The authors have no commercial interest in this device and received no remuneration of any kind in the development and evaluation of this device.

  • Provenance and peer review Not commissioned; internally peer reviewed.

Linked Articles