Article Text

Download PDFPDF
Deep learning in congenital heart disease imaging: hope but not haste
  1. Rhodri Davies1,2,
  2. Sonya V Babu-Narayan3,4
  1. 1Barts Heart Centre, St Bartholomew's Hospital, London, UK
  2. 2Institute of Cardiovascular Science, University College London, London, London, UK
  3. 3Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK
  4. 4National Heart and Lung Institute, Imperial College, London, UK
  1. Correspondence to Dr Rhodri Davies, Barts Health NHS Trust, London E1 1BB, UK; rhodri.davies2{at}nhs.net

Statistics from Altmetric.com

Deep learning promises to revolutionise cardiac imaging with more accurate and more reproducible interpretation delivered almost instantaneously. But transferring promise into clinical delivery is a considerable task and we lag behind other fields.

The growing demand for cardiac imaging due to an ageing population with growing disease burden is not matched by an increased supply of clinicians trained in image interpretation. This is exacerbated in congenital heart disease due to increasing survivorship, disease complexity and paucity of available expertise. Deep learning has revolutionised the field of image analysis and there are now systems capable of automating cardiac image segmentation. Eliminating tedious tasks such as measuring structures on images can reduce burn-out and refocus clinicians on higher-level functions, the doctor–patient relationship and providing more empathic care.

But deep learning promises much more: it has the potential to improve on expert human image interpretation, and this is being realised with reports of better-than-human performance for breast cancer detection.1 We, as clinical experts, are not as good as we think we are at image interpretation—the minimal detectable change when ejection fraction is measured by an expert on cardiac MRI is 8.7%, mostly due to poor repeatability.2 Deep learning has potential for more accurate and more precise analysis where confidence in reported results can be quantified. Benefits could cascade through healthcare systems, with fewer repeated tests, less follow-up, and ultimately better clinical outcomes.

Cheap hardware and easy-to-use open-source software have made deep …

View Full Text

Footnotes

  • Contributors RD and SVB-N coauthored the paper, with RD leading the technical and SVB-N leading the clinical aspects.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned; internally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Congenital heart disease
    Gerhard Paul Diller Stefan Orwat Julius Vahle Ulrike M M Bauer Aleksandra Urban Samir Sarikouch Felix Berger Philipp Beerbaum Helmut Baumgartner German Competence Network for Congenital Heart Defects Investigators Gunter Kerst jaime F Vazquez-Jimenez Dimitrios Gkalpakiotis Vazquez-Jimenez Andrea Schedifka Gernot Buheitel Joachim Streble Kai Thorsten Laser Eugen Sandica Burkhard Trusen Felix Berger Oliver Miera Stanislav Ovroutski Björn Peters Katharina Schmitt Stephan Schubert Joachim Photiadis Felix Berger Bernd Opgen-Rhein Katja Weiss Christoph Berns Carl-Christian Blumenthal-Barby Thomas Boeckel Guido Haverkämper Andreas Kästner Heike Koch Christian Köpcke Frank Streichan Jens Timme Birgit Franzbach Gabriela Senft Frank Beyer Klaus Winter Johannes Breuer Bahman Esmailzadeh Martin Schneider Boulos Asfour Jens Bahlmann Eberhard Griese Trong Phi Lê Joachim Hebe Jan-Hendrik Nürnberg Annette Magsaam Ronald Müller Ludger Potthoff Renate Voigt Tim Krüger Hubert Gerleve Ulrich Kleideiter Dirk Schneider-Kulla Jürgen Krülls-Münch Elmo Feil Thomas Menke Martin Lehn Antje Heilmann Helge Tomczak Otto N. Krogmann Gleb Tarusinov Michael Scheid Ertan Mayatepek Frank Pillekamp Artur Lichtenberg Christiane Terpeluk Bruno Kolterer Sven Dittrich Ulrike Gundlach Robert Cesnjevar Ulrich Neudorf Geert Morf Anoosh Esmaeili Stephan Backhoff Brigitte Stiller Friedhelm Beyersdorf Johannes Kroll Nicole Häffner Jannos Siaplaouras Antje Masri-Zada Christian Jux Andreas Böning Hakan Akintürk Thomas Paul Matthias Sigler Theodor Tirilomis Gabriele Schürer Johannes Hartmann Ralph Grabitz Uta Liebaug Claudius Rotzsch Rainer Kozlik-Feldmann Jörg Sachweh Arlindo Riso Stefan Renz Andreas Schemm Bernd Friedrich Otmar Schlobohm Philipp Beerbaum Dietmar Böthig Alexander Horke Johann Bauersachs Mechthild Westhoff-Bleck Matthias Gorenflo Matthias Karck Tsvetomir Loukanov Hermann Schrüfer Martin Wilken Hashim Abdul-Khaliq Tanja Rädle-Hurst Axel Rentzsch Hans-Joachim Schäfers Hagen Reichert Thomas Kriebel Arnulf Boysen Anselm Uebing Joachim Thomas Cremer Jens Scheewe Regina Buchholz-Berdau Peter Möller Wolfgang Ram Konrad Brockmeier Gerardus B. W. E. Bennink Alex Gillor Tim Niehues Peter Terhoeven Steffen Leidig Ingo Dähnert Peter Kinzel Martin Kostelka Liane Kändler Martin Bethge Stefan Köster Christoph Schröder Jens Karstedt Uwe Seitz Christoph Kampmann Christian-Friedrich Vahl Frank Stahl Mojtaba Abedini Joachim Müller-Scholden Peter Ewert Alfred Hager Harald Kaemmerer Nicole Nagdyman Jörg Schoetzau Oktay Tutarel Rüdiger Lange Jürgen Hörer Nikolaus A. Haas Lale Rosenthal Michael Hauser Alexander Roithmaier Hans-Gerd Kehl Edward Malec Helmut Baumgartner Gerhard Diller Roswitha Bahle Gerald Hofner Stefan Zink Roland Reif Helmut Singer Christoph Parlasca Matthias W. Freund Michael Schumacher Oliver Dewald Christine Darrelmann Reinald Motz Olaf Willmann Norbert Schmiedl Peter Quick Dirk Hillebrand Stephan Michele Eiselt Torsten Nekarda Michael Eberhard Georg Baier Frank Uhlemann Ioannis Tzanavaros Alexander Beyer Gudrun Binz Steffen Hess Thomas Teufel Ronald-Peter Handke Michael Hofbeck Renate Kaulitz Ludger Sieverding Christian Schlensak Christian Apitz Michael Kaestner Christoph Kupferschmid Jürgen Holtvogt Carl-Friedrich Wippermann Andreas Heusch Johannes Wirbelauer Wolfgang Brosi