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Bridging the gap: understanding sex differences in low-density lipoprotein cholesterol control through the lens of integrated data analysis and behavioural sciences
  1. M Julia Machline-Carrion
  1. Medical Affairs, epHealth, London, UK
  1. Correspondence to Dr M Julia Machline-Carrion, Medical Affairs, epHealth, London, UK; mjuliacarrion{at}

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Low-density lipoprotein cholesterol (LDL-C) is a well-known risk factor for cardiovascular disease, a leading cause of morbidity and mortality worldwide. Traditionally, guidelines for LDL-C management have been largely uniform across genders, with little consideration given to potential sex-based differences in response to treatment. In the realm of healthcare, understanding the intricacies of disease management is paramount to providing effective care. By analysing real-world data (RWD) from a representative population, the study by Kiss et al1 sheds light on sex differences in the prescription of high-intensity statins and achievement of LDL-C target levels within primary care populations and contributes towards personalised and equitable healthcare.

As integrated data analysis emerges as a powerful tool in this endeavour, this study using healthcare records from a population-based network of electronic healthcare data banks that combines data from different primary and secondary healthcare settings in the Netherlands (the PHARMO Data Network)2 offers insights into population-level trends and disparities in healthcare delivery. By aggregating data from various sources such as electronic health records and pharmacy records, healthcare providers gain a comprehensive view …

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  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests MJM-C received research grants from Novartis, Ipsen, GSK and Amgen.

  • Provenance and peer review Commissioned; internally peer reviewed.

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