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Management of bicuspid aortic valve disease in the transcatheter aortic valve implantation era
  1. Marjan Jahangiri1,
  2. Bernard Prendergast2
  1. 1Department of Cardiac Surgery, St George's University Hospitals NHS Foundation Trust, London, UK
  2. 2Department of Cardiology, Guy's and St Thomas' NHS Foundation Trust, London, UK
  1. Correspondence to Professor Marjan Jahangiri, Department of Cardiac Surgery, St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK; marjan.jahangiri{at}stgeorges.nhs.uk

Abstract

In an era of rapidly expanding use of transcatheter aortic valve implantation (TAVI), the management of patients with bicuspid aortic valve (BAV) disease is far less well established than in those with trileaflet anatomy. Results of isolated surgical aortic valve replacement are excellent in suitable patients, and surgery also allows treatment of concomitant pathology of the aortic root and ascending aorta that is frequently encountered in this cohort. Conversely, TAVI provides an excellent alternative in older patients who may be unsuitable for surgery, although outcomes in BAV disease have only been reported in relatively small non-randomised series. Here, we discuss the pertinent literature on this topic and outline contemporary interventional treatment options in this challenging setting.

  • Aortic Valve Insufficiency
  • Aortic Valve Stenosis
  • Congenital Abnormalities

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Footnotes

  • MJ and BP contributed equally.

  • Contributors Both authors contributed equally. MJ is the guarantor.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; externally peer reviewed.