200 e-Letters

published between 2007 and 2010

  • ECG clues to an unusual diagnosis
    F. Russell Quinn

    To the Editor.

    We read with interest the Image in Cardiology by Brown & Agarwal documenting the phenomenon of T wave memory in a patient with Ebstein's anomaly who presented with tachycardia[1]. We would be interested to know whether any further investigation for her dysrhythmia was performed. The ECGs presented strongly suggest that she may have an atriofascicular bypass tract - an unusual variant of pree...

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  • RE: Large thrombus burden in acute myocardial infarction: successful use of distal protection device following failure of thrombus aspiration
    Adrian Iancu

    We read with great interest the article published by Mathew G.D. Bates in your journal [1]. We congratulate the authors for the original management of this case. In similar cases of large thrombus, we have administered intrathrombus eptifibatide through the 3F Twin Pass catheter (Vascular Solutions, Minnesota 55369 USA), and then performed thrombus aspiration. Finally, conventional stenting was performed. Postprocedural,...

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  • Review protocols should be registered
    Tom Quinn

    Dear Editor

    Heras and her colleagues make a good point.[1] Perhaps those planning systematic reviews should be required by journal editors to register their protocol on a central database, as we currently do for Cochrane reviews? Authors should also perhaps be required to state what they consider their review adds (e.g. that previous reviews were methodologically flawed, reported inadequate information on search strate...

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  • Propafenone contraindicated in the elderly?
    Charles JHJ Kirchhof
    Dear Editor With great interest we read the paper of Alboni et al. [1]. The investigators studied intravenous class Ic antiarrhythmic drug administration (propafenone and flecainide) as a predictor for adverse effects when used in a 'pill-in-the-pocket'¢ regimen (PITP). Alboni and colleagues suggest that intravenous administration of flecainide or propafenone for pharmacological conversion of AF to sinus rhy...
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  • Propafenone contraindicated in the elderly?
    Paolo Alboni

    We thank Drs Kirchhof, Crijns and van Gelder for their interest in our paper (1) referring pill-in-the-pocket treatment of recent-onset atrial fibrillation (AF). The study was interrupted on the recommendation of the data-and safety-monitoring committee because the results suggested that the intravenous administration of flecainide or propafenone does not predict the occurrence of adverse effects after a loading oral dos...

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  • What is the best dose of aspirin in association with P2Y12 antagonists?
    Marco Cattaneo

    In their Viewpoint article, Warner et al hypothesized that the administration of aspirin to patients who are treated with potent antagonists of the platelet P2Y12 receptors might increase cardiovascular risk.1 The authors' hypothesis is based on the observation that P2Y12 antagonists inhibit the platelet production of thromboxane A2 (TxA2) (which would render the use of aspirin superfluous), and on the consideration tha...

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  • Authors reply: Low sex hormones in heart failure
    Gulmisal Guder

    In their recent editorial in this Journal Theodoraki and Bouloux [1] question the cut-off values employed in our article on the association between circulating androgens and mortality risk in heart failure (HF).[2] While we (according to our local Central Hospital Laboratory) defined androgen deficiency by total testosterone values <180 ng/dl for patients >50 years and 260 ng/dl for younger patients, and by free te...

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  • The patient with hypertrophic cardiomyopathy has a family
    Imke Christiaans

    To the editor: With great interest we have read the paper on hypertrophic cardiomyopathy by ten Berg et al.1 As the paper has an educational aim, we would like to address some minor misconceptions that could have major implications.

    Genotyping in HCM to establish a molecular diagnosis in HCM patients can indeed probably not be used to guide prognosis or therapy. However, it has been proven to be a more cost-effe...

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  • Cardiac imaging training in the United Kingdom
    Edward D Nicol


    Cardiac imaging training in the United Kingdom

    It was with interest that we read the featured correspondence from Rajani et al (ref). We entirely agree with their assertion that there is a growing need for multi-modality cardiac imagers and acknowledge their concerns about the lack of structured "in-programme" training opportunities, such as cardiac imaging fellowships, to support this requireme...

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  • Air Pollution, Weather, and ischaemic cerebral and cardiac events: Methodological Considerations
    Ivy Shiue

    It is with great interest to read a recent article of " Evidence of the role of short-term exposure to ozone on ischaemic cerebral and cardiac events: the Dijon Vascular Project (DIVA)" by Henrotin et al.1 They detailed addressed the analysis procedure and considerations and presented findings on the relationship of air pollution and ischaemic cerebral and cardiac events in a large population-based setting. However, a few...

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