159 e-Letters

published between 2012 and 2015

  • Re:Ischaemic conditioning: paving the pathway to clinical translation
    Heerajnarain Bulluck

    We thank Iliodromitis and colleagues for their interest in our review article1. Providing a comprehensive account of the extensive literature in this field has been a very challenging task. We are aware of their previous work2 3 on the feasibility of ischaemic postconditioning (IPost) in acute coronary syndrome. Of note, this was a small study of 37 patients and only included a total of 6 patients with non-ST elevation myoc...

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  • Radiation exposure considerations relevant to using propofol for nurse-led sedation in cardiological practice
    Aaron Conway
    The authors should be congratulated for providing timely guidance about the use of propofol for nurse-led sedation in modern cardiological practice.[1] The broad scope of the article surely prevented presentation of a comprehensive set of recommendations. However, a particularly important issue for the nursing staff who would be involved, which was not addressed in this article, deserves focused attention. A recent study reported...
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  • Re: "There Truly is an Obesity Paradox"
    Carl J. Lavie

    I appreciate Dr. Stovitz's interest in our editorial and on the topic of the "Obesity Paradox". As I stated in my book, The Obesity Paradox,1 a paradox can be defined "as a statement that is seemingly contradictory or opposed to common sense and yet is perhaps true". Based on this, Stovitz could have better titled his letter as "True, true, and is a true paradox." As we previously demonstrated,2-4 despite that obese wit...

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  • Ischaemic conditioning: paving the pathway to clinical translation
    Efstathios K. Iliodromitis

    The timely restoration of flow in the culprit coronary artery lesion remains the cornerstone of treatment in patients with evolving myocardial infarction but with the inevitable cost of reperfusion injury. Cardiac ischaemic conditioning (IC) is capable of reducing the extent of final infarct size, but its actual benefit in improving clinical outcomes remains to be established. In their excellent review article published...

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  • Complete revascularization in STEMI
    Ramez S Nairooz

    Cover Letter

    Complete revascularization in STEMI

    a Ramez Nairooz, MD, b Srihari S Naidu, MD.

    a Division of Cardiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas; b Division of Cardiology, Winthrop University Hospital, Mineola, New York.

    Funding: None Conflicts of interest: none Word Count: 325 Corresponding author & (address for reprints) Ramez Nairooz, MD...

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  • The key role of the right ventricle in the pathogenesis of acute pulmonary oedema
    David H MacIver

    The article entitled "The pathophysiology of hypertensive acute heart failure"[1] provides a contemporary review of mechanisms involved in the development of acute pulmonary oedema (APO). We wish to highlight the potential key role of the right ventricle in the pathogenesis of APO.[2]

    APO is often thought to result from backward pressure where a disease of the left ventricle causes the left ventricular end-diasto...

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  • True and true, but not a paradox
    Steven D Stovitz

    The journal, Heart, recently published a meta-analysis(1) and a commentary(2) on the association of obesity and mortality in patients with Coronary Heart Disease (CHD). Lavie begins his commentary with a story of two hypothetical patients with CHD. One has a BMI of 23 kg/m2 (normal) and the other has a BMI of 32 kg/m2 (obese).(2) Lavie asks about their prognosis. The meta-analysis by Wang et al(1) suggests that the obese...

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  • Correspondence: A not so typical pericardial effusion case....
    George A. Lazaros

    To the Editor: We have read with interest the article of Miranda WR and coauthors1, in which a case of effusive-constrictive pericarditis is presented. This is a comprehensive and educational case that provides clinicians with a valuable message. Some points, however, require additional clarification in order to further strengthen the impact of this case. In particular, it is mentioned in the introduction that the patien...

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  • Importance of the UK health care model for success in cardiovascular disease control compared the health care model in Turkey
    Fatih Yalcin

    We read the paper of Bhatnagar P. et al. 1 and were impressed by great success of the UK health care on control of cardiovascular disease (CVD). In the UK during last decade, CVD decreased from top to 2nd row on mortality of men in whom, lipid lowering drugs were the most prescribed medicine. 1 In this report, importance of primary care and increased number of less invasive approaches like angioplasty compared to surge...

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  • Review underestimates cardiovascular disease prevalence
    Michael Soljak

    Dear Editor

    In their review of the epidemiology of cardiovascular disease (CVD) in the UK, Bhatnagar et al considerably underestimate the prevalence of CVD.[1] They used data from the Clinical Practice Research Datalink (CPRD), an extract of primary care electronic health records (EHRs) of a representative sample of patients registered with UK general practices, and data from the Quality & Outcomes Framewor...

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