147 e-Letters

published between 2010 and 2013

  • On the cost-effectiveness of primary angioplasty
    Giovanni Melandri

    Sir, in their elegant evaluation of primary angioplasty vs thrombolysis cost-effectiveness, Wailoo and Coll. conclude that primary angioplasty-based care is highly likely to be costeffective, particularly if patients are admitted directly to the cardiac catheter laboratory 1. These conclusions will certainly trigger the opening of new catheterization laboratories across the UK and elsewhere as well. As a consequence, the...

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  • "Pill in the pocket" treatment for recent-onset atrial fibrillation
    Obiora Anusionwu

    Paolo Alboni et al concluded that the patient's tolerance of intravenous administration of flecainide or propafenone does not seem to predict adverse effects during out-of-hospital self administration of these drugs (1). However, it is important to note that the number of patients in the study were only 122 with a 5% incidence of major adverse effects. Patients without structural heart disease would benefit from propafeno...

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  • Gender and Myocardial Infarctions
    Marina B Guerra
    Our ischaemic cardiopathy study group have read with interest the article written by Lawesson et al (1). First of all, the occurrence of ST-elevation myocardial infarction in young women is rare and the tobacco nocive role is well established in the medical literature. However, we would like to emphasize that smoking in women is growing nowadays. According to World Health Organization, there are 1,2 billion smokers around the wo...
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  • To the Editor
    Jan-Henk E. Dambrink

    With great interest we have read the article by Politi et al(1) on revascularisation of patients with ST-elevation myocardial infarction and multivessel disease. The authors are to be complimented with the largest randomised trial on this subject, with the longest follow-up.

    However, we question whether this study is the 'justification for complete revascularisation at the time of primary angioplasty', as the p...

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  • Endothelial Dysfunction and Necrotic Core Plaques
    Scott W Murray

    To the editor: I would like to thank Dr Lerman for his reply to our measurement question [1]. I am acutely aware of Dr Lerman's fantastic research pedigree and the excellent ground breaking work produced by the Mayo clinic group, which swamps my paltry contribution to this area. However, My specific question in the previous letter [2] was not related to the ability of the IVUS-VH classification tree to determine plaque...

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    Inigo Lozano

    We have read with interest the article written by Piscione et al1 related with direct stenting. The authors have performed a meta-analysis of 24 randomised controlled trials of direct stenting vs. stenting with predilatation and the conclusion is a 23 % reduction in the odds of myocardial infarction. In our opinion, direct stenting should be the approach of choice in all the susceptible cases because this important bene...

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  • Coronary Sinus Reducer Stent
    Yoav Paz

    Editor, we read with great interest the article "NICE evaluation of transmyocardial laser revascularisation and percutaneous laser revascularisation for refractory angina [1].

    The authors described a variety of treatment options for patients suffering from refractory angina pectoris (RAP). However, a very important, evolving innovation is missing: coronary sinus intervention (CSI).

    Coronary venous int...

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  • adiponectin and LV diastolic dysfunction
    professor viroj wiwanitkit
    Editor, I read the recent publication by Uno et al [1]. Uno et al concluded that adiponectin is an indicator of LV diastolic dysfunction in patients with HCM [1]. There are some points to be concerned before using this conclusion. First, only 26 cases were investigated in this work and this might be a weakness in statistical analysis. Second, there are several practical concerns on the measurement of adiponectin starting from samp...
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  • Provincial Letter
    RK Mohindra
    Shaw D and Conway DI (1) correctly identify that a fact neither proved nor disproved lies at the heart of both Pascalâ₉„¢s wager and the National Institute of Clinical Excellence (NICE) guidance in relation to the use of antibiotic (abx) prophylaxis for infective endocarditis (IE) . The no lose argument is no match winner for NICE because cardiologists are all too keenly aware that antibiotics kill as sure...
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  • Long-term dual antiplatelet therapy after percutaneous coronary
    Andrea Messori

    The statistics of propensity adjustment, that Harjai et al.(1) have used with some modifications, is a recognised tool to increase the value of non-experimental data(2,3).

    However, these authors have used propensity statistics less efficiently than other studies in this area have done(2,3). In fact, propensity statistics has only been introduced by Harjai et al. in their multivariate regression analysis, but...

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