eLetters

174 e-Letters

published between 2001 and 2004

  • Letter to Editor
    C Richard Conti

    Dear Editor

    , When I received the September issue of Heart, I was pleased to read an article by Galasko and colleagues (Heart 2001; 86:271-276) on the prospective comparison of echocardiographic wall motion score index and radionuclide ejection fraction in predicting outcome following acute myocardial infarction. In their introduction, they indicated that no study has directly compared wall motion score index and l...

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  • Re: Cardiomyopathy in HIV disease. Is Nutritional State a factor?
    Giuseppe Barbaro
    Dear Editor

    A variety of potential causes have been proposed for HIV-associated cardiomyopathy, including myocardial infection with HIV itself, opportunistic infections, viral infections, autoimmune response to viral infection, drug-related cardiotoxicity, prolonged immunosuppression and nutritional deficiencies [1]. Nutritional deficiencies are common in HIV infection [2,3]. Poor absorption and diarrhea can both lead to d...

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  • Re: Implementation of NICE guidance on the use of implantable cardioverter defibrillators
    Nick Gall
    Dear Editor,

    We thank Drs Plummer and McComb for their interest in our estimate of the implications of the recently published NICE guidelines for United Kingdom electrophysiology centres [1]. We agree that an assessment of the workload implications of these guidelines is important for resource planning.

    Using data gathered in clinical trials designed for different ends will always require assumptions and can therefor...

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  • Cardiomyopathy in HIV disease. Is Nutritional State a factor?
    SW Yusuf
    Dear Editor

    Barbaro G et al have nicely described the cardiological manifesations of HIV infection[1].However no mention is made about the concomitant nutritional deficiencies, which may contribute to cardiomyopathy in these cases.Selenium deficiency,a well known cause of reversible cardiomyopathy(Keshan disease)[2],has been linked to cardiomyopathy in HIV disease[3].Selenium is an essential component of glutathione p...

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  • Evaluation of the EMMACE model in a US population with non-ST elevation acute myocardial infarction
    Emmanouil Brilakis
    Dear Editor,

    We read with great interest the recent article by Dorsch and Lawrance.[1] Using data from the EMMACE (Evaluation of Methods and Management of Acute Coronary Events) study they derived a simple model for prediction of 30-day mortality in patients with acute myocardial infarction. Their model included age, heart rate, and systolic blood pressure and had very good predictive accuracy with areas under the receiver o...

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  • Eevated concentrations of macrophage colony stimulating factor in unstable angina
    Uichi Ikeda
    Dear Editor

    We read with great interest the article by Rallidis et al. [1] that elevated concentrations of macrophage colony stimulating factor (MCSF) predict a worse short term prognosis in patients with unstable angina. Recent studies have clarified the significance of monocyte-related cytokines such as MCSF in the development of atherosclerosis, atheromatous plaque rupture and restenosis after coronary angioplas...

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  • Implementation of NICE guidance on the use of implantable cardioverter defibrillators
    C J Plummer

    Dear Editor,

    The activity monitoring analysis of the UK-HEART study published by Gall et al. [1] is very welcome. They calculate that screening of 551 ambulant patients with stable heart failure according to NICE guidance [2] would result in 142 electrophysiology studies (EPS) and the implantation of 50 implantable cardioverter defibrillators (ICDs). Thus 9% of their population were found to have a primary preve...

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  • Previous experience with long axis shortening in aortic stenosis
    J G Dumesnil
    Editor,

    We have read with interest the article by Takeda et al.[1]. Our group has previously observed that patients with aortic stenosis often have selective decreases in ventricular longitudinal shortening and wall thickening concomitant with normal fractional shortening and ejection fraction [2-4]. In the same studies, we also postulated that since subendocardial fibres are oriented longitudinally, this selective dec...

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  • Anatomical terminology
    Robert H Anderson

    Saliba and colleagues are to be congratulated on their study to establish the quality of life in the setting of complex congenital cardiac malformations. My comments are in no way intended as a criticism of their excellent and much-needed investigation. It is depressing, however, to note that anatomical description lags so far behind the sophisticated evaluation of status of health. It is very likely that none of the patien...

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  • OMP Jolobe
    Dear Editor

    The occurrence of drug-related prerenal uraemia and, hence, hyperkalemia [1,2] is an entirely predictable outcome if the precaution is not taken to reduce the dose of loop diuretics when sprironolactone is added to existing angiotensin converting enzyme (ACE) inhibitor therapy. This given the fact that the coprescription of all three modalities (ie spironolactone, loop diuretics, and ACE inhibitors) can...

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