145 e-Letters

published between 2011 and 2014

  • Mistaken conclusions
    Tom Marshall

    To whom it may concern,

    The meta-analysis reported by Lasserson et al provides evidence that half of the effect of antihypertensive treatment on blood pressure takes place within the first week of treatment. [1] There is no reason to doubt these findings. However the analysis does not support the conclusion that "estimation of maximal effect could be made between 1 and 2 weeks after initiation of antihypertensi...

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  • Systemic inflammation sometimes displays paradoxical outcomes
    Carr J Smith

    To the editor: The very interesting study by Logue et al. (2011) on a group of middle- aged, hypercholesterolic men with no prior history of diabetes or CVD, recently reported that obesity is associated with fatal coronary heart disease (CHD), but not non -fatal CHD independently of traditional CVD risk factors. The authors hypothesize that since excessive adipose tissue is known to secrete inflammatory mediators, that in...

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  • MIBG and Risk Stratification
    A Salih

    I would like to mention the place of MIBG as other modality of Cardiac Imaging for risk stratification of patients with heart failure in need for ICD; see Bax et al, Cardiac Sympathetic Denervation Assessed With 123-Iodine Metaiodobenzylguanidine Imaging Predicts Ventricular Arrhythmias in Implantable Cardioverter-Defibrillator Patients

    J Am Coll Cardiol, 2010; 55:2769-2777, doi:10.1016/j.jacc.2009.12.066...

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  • Improving echocardiographic estimation of pulmonary vascular resistance
    Corrado Magnino

    We appreciated the paper by Dahiya et al. attempting to improve non- invasive estimation of pulmonary vascular resistance (PVR)(1). However, some points deserve few comments. 1. The new formula (PVRc) compared to the previous one by Abbas et al.(2) (PVRe) includes E/e' ratio, in order to take into account pulmonary capillary wedge pressure (PCWP) and better estimate transpulmonary gradient. E/e' is a ratio, but needs to...

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  • Heart-type fatty acid-binding protein in the early diagnosis of acute myocardial infarction: a systematic review and meta-analysis
    James A. Shand

    To the Editor

    We read with interest the systematic review and metanalysis by Bruins Slot et al concerning early diagnosis of myocardial infarction using heart type fatty acid binding protein (HFABP) (1). We agree with their summary that used in isolation, HFABP may not offer a diagnostic advantage over the current troponin standard. However it should be noted that in 5 of the included studies, constituting 1573 pa...

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