eLetters

200 e-Letters

published between 2007 and 2010

  • Pulmonary artery stiffness in arterial switch patients
    Tomoaki Murakami

    Dear Editor,

    The recent study by Grotenhuis and colleagues demonstrated the increased peak flow velocity across the pulmonary trunk, right ventricular hypertrophy and right ventricular relaxation abnormalities in patients after the arterial switch operation (1). The authors argued that one of the possible causes of the increased peak flow velocity was local scar tissue with loss of pulmonary artery diste...

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  • Socioecomonic status and cardiovascular disease risk
    Jolanta Mieczkowska

    Dear Editor,

    We congratulate Dr A Steptoe and associates on their extensive epidemiological research concerning the cardiovascular risk and its association with the pathogen burden depending on the socio-economic status (1). Since the middle of the 20th century, the cardiovascular risk in the populations of Europe and the United States has shown a reverse dependence on the economic and professional status. Many rese...

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  • Management includes primary prevention
    M Justin S Zaman

    Dear Editor,

    Though the mandate of Karthikeyan et al’s article is the management of manifest coronary disease, primary prevention at the population level should not be ignored. India is rapidly urbanising, and urban India shows marked increases in both coronary heart disease prevalence and risk factors when compared with rural settings. (1)Though coronary risk factors tend to be concentrated in those of higher s...

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  • Author's Response
    Wojtek Wojakowski

    Dear Editor,

    Thank you for forwarding us the leter of Dr Rochefort and his kind comments on the paper. He has made a good point, and of course he is right about the increased mobilization of the MSC in experimental hypoxia, which he confirmed in an elegant experiment. Table 3 contains an typing error, which we are sorry to have missed during proofreading. The correct meaning of the sentence is "Increase of bone ma...

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  • Hypoxia-induced Mesenchymal Stem Cells mobilization
    Gael Y Rochefort

    Dear Editor,

    I read with great interest the review by Wojakowski et al about the mobilization of bone marrow-derived stem/progenitor cells during acute coronary syndromes.1 The contribution of such cells, including hematopoietic stem cells, mesenchymal stem cells (MSCs), endothelial progenitor cells and other poorly defined progenitors, is well in coronary heart diseases. I agree this review discusses and summa...

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  • Care with Single Coil AICD leads
    Stephanie L Curtis

    Dear Editor,

    Adamson and Nelson-Piercy give a thorough overview of arrhythmias in pregnancy1. However they mention that the presence of an automated implantable cardio-defibrillator (AICD) poses no risk to the fetus as, even after device therapy, ‘the electrical field to which the fetus is exposed is minimal’.

    We recently cared for a 23 year old patient with hypertrophic cardiomyopathy who had an AICD...

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  • Authors Response
    Shane George

    Dear Editor,

    We thank Drs Mclaren et al. for their interest in our study.

    Firstly, we chose Vancomycin as we wished to use an antistaphylococcal drug that had been studied in cardiac surgical patients. Additional rifampicin was used in an attempt to prevent resistance developing. Clearly the strategy was successful as we did not see any increase in resistant organisms during, or for the 2 years after,...

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  • Authors Response
    Bente Grüner Sveälv

    Dear Editor,

    We thank Dr. Ballo and colleagues for their interesting comments on our article. In agreement with our study, Ballo et al show a nonlinear association between circumferential midwall and longitudinal LV systolic function in patients with hypertension [1]. It is particularly noteworthy that this nonlinear association is apparent in two different study populations. The patients in our study were suff...

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  • Antibiotic prophylaxis in cardiac surgery
    Graeme MacLaren

    Dear Editor,

    The recent study by Dhadwal et al. (1) has a number of weaknesses which merit discussion. The study appears to have been initiated by a “perceived increase in crude infection rates” but the organisms responsible for this increase were not presented. Unless there was a high incidence of infection with resistant organisms such as methicillin- resistant Staphylococcus aureus (MRSA) prior to study comme...

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  • Prognostic value of left ventricular long-axis versus short-axis systolic function in heart failure
    Piercarlo Ballo

    Dear Editor,

    Grüner Sveälv et al.(1) recently found that left ventricular (LV) long-axis atrioventricular plane displacement (AVPD) in heart failure (HF) patients was linearly correlated with short-axis fractional shortening (LVFS) in the lower range of AVPD, but not in the higher range of AVPD. They also observed that decreasing AVPD quartiles showed a stepwise association with worsening prognosis. Notably, a sim...

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