eLetters

200 e-Letters

published between 2007 and 2010

  • Prosthetic Heart Valve Thrombosis. Is thrombolysis really still controversial?
    Jose Santos-Gracia

    Dear Editor,

    We have read with great interest the article by Roudaut et al entitled "Thrombosis of prosthetic heart valves: Diagnosis and therapeutic considerations" published in the last issue of your journal.(1) According to the authors, the first therapeutic consideration in obstructive left-sided prosthetic valve thrombosis (PVT) should be surgery and thrombolysis should be reserved for patients with contrain...

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  • Antimicrobial prophylaxis for endocarditis: emotion or science?
    David H Roberts

    Dear Editor,

    The debate on the role of antimicrobial prophylaxis to prevent infective endocarditis (IE) has intensified as a consequence of the recently published guidelines from the Working Party of the British Society for Antimicrobial Chemotherapy (BSAC). In the review by Ashrafian and Bogle, reference is made to the dental community’s satisfaction with these new guidelines, highlighting a “victory for scien...

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  • Antimicrobial prophylaxis for endocarditis: Emotion or science
    John A C Chalmers

    Dear Editor,

    As cardiac surgeons we read and reread the editorial by Ashrafian and Bogle initially with interest and subsequently bemusement looking for a definitive message. The title was clear enough; the editorial was not.

    The conclusion that good practice will be served if “patients are adequately counselled on the benefits of good dental hygiene and a discussion is undertaken and documented on the ri...

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  • Dentistry and endocarditis: beyond antibiotics
    Kenneth A Hoekstra, PhD

    Dear Editor,

    In the report by Ashrafian1 and Bogle, the authors highlight new recommendations by the British Society for Antimicrobial Chemotherapy to limit prophylaxis to high-risk patients with previously documented endocarditis or surgical shunt/valve procedures (1). Although dental prophylaxis have an impact on systemic disease, they do not eliminate bacteremia altogether. Thus, in addition to antibiotic the...

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  • Antimicobial Prophylaxis for Endocarditis: Emotion or Science?
    David R Ramsdale

    Dear Editor,

    The editorial by Ashrafian and Bogle[1] suggests that the authors have little clinical experience in the management of patients with infective endocarditis (IE). The body of cardiologists and cardiac surgeons in Europe, North America and the UK would disagree that the BSAC guidelines are important or “a step in the right direction” and almost certainly the guidelines will be disregarded by the rest o...

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  • Hepatic nodules in patients with a failing Fontan circulation
    Giuseppe Brancatelli

    Dear Editor,

    with respect to the article on hepatic changes in the failing Fontan circulation by Kiesewetter et al (1), we would like to respectfully point out that large hypervascular regenerative nodules arising in the setting of vascular hepatic disorders (especially Budd-Chiari syndrome) should be considered as a different entity in comparison to regenerative nodules found in cirrhotic liver. At our referra...

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  • Effect of weather conditions on the mortality of heart attacks in Hungary
    Ildikó Kriszbacher

    Dear Editor,

    We read with great interest the very important article by Dilaveris et al about the climate impacts on myocardial infarction deaths in Athens, Greece [1]. Several reports have already proved that the number of deaths related to acute myocardial infarction (AMI) shows a seasonal variation, with a peak in winter, and a lowest number of mortality rates during the months of summer [2,3,4]. The effects o...

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  • Right ventricular reverse remodelling after sildenafil in pulmonary arterial hypertension
    Ze-Zhou Song

    Dear Editor,

    We read with great interest the study by Wolferen et al1, which confirmed that addition of sildenafil reversed right ventricular (RV) dilatation and hypertrophy in pulmonary arterial hypertension (PAH) patients already receiving treatment and that these positive effects on RV structure and function occurred in parallel with improvements in exercise capacity and N-terminal pro-brain natriuretic peptide (NT-...

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  • Continuous wave Doppler based cardiac output in immersion in swimming athletes
    Karsten Knobloch

    Dear Editor,

    I read with great interest the recent report from Schmid and coworkers regarding the hemodynamic changes induced in water, which is of special interest among patients with deteriorated cardiac function. The hypothesis is interesting, however the methods used for cardiac output determination in a swimming pool have to be discussed. Schmid used an inert gas rebreathing method using an infrared photoa...

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  • Acute Coronary Syndrome. A Progression of Pre-Metabolic Syndrome and the Asian Paradox
    Ram B Singh

    Dear Editor,

    We injoyed very much the most interesting study by Teo et al (1). Acute coronary syndromes(ACS) and coronary risk factors; hypertension, hyperlipidemia,obesity and type 2 diabetes have become a major health problem in Asia with economic development,due to interaction of gene and environmental factors.(2) Overswinging,that is an excessive circadian variation in blood pressure (BP) has been associated with...

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