215 e-Letters

published between 2004 and 2007

  • IIb/IIIa inhibition in the elderly: do they have a role after pre-treatment with clopidogrel?
    Arun Kalyanasundaram

    Dear Editor,

    PRISM: ASA + heparin, ASA + tirofiban

    PRISM-PLUS: ASA + heparin, ASA + heparin + tirofiban

    PARAGON: ASA + heparin + lamifiban, ASA + lamifiban, ASA + heparin

    PURSUIT: ASA + heparin, ASA + heparin + eptifibatide

    GUSTO-IV ACS: ASA + heparin, ASA + heparin + abciximab

    PARAGON-B: ASA + heparin, ASA + heparin + lamifiban

    A meta-analysis by Hernandez...

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  • Re: Intravenous magnesium in rhythm control of atrial fibrillation
    Kwok M. Ho

    Dear Editor,

    Thank you for the interest of Dr. Srikanth Vallurupalli on our meta- analysis. In response to his comments on rhythm conversion by intravenous magnesium, I would like to clarify the results of our meta-analysis to avoid misunderstanding.
    In the analysis of the efficacy of magnesium in converting atrial fibrillation to sinus rhythm, magnesium was compared to a placebo-control group...

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  • When Quality Hurts
    Michael R Ward

    Dear Editor,

    The article by Bridgewater et al “Has publication of cardiac surgery outcome data been associated with changes in practice in Northwest England? An analysis of 25,730 patients undergoing CABG surgery under 30 surgeons over 8 years.” (1) has received significant international attention with headlines around the world. However before the quality junkies lapse into a swoon of self congratulation over...

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  • Intravenous magnesium in rhythm control of atrial fibrillation
    Srikanth Vallurupalli

    Dear Editor,

    I read with interest the meta analysis by Ho et al on the use of intravenous magnesium to treat acute onset atrial fibrillation.

    In their analysis of the efficacy of magnesium in the conversion of atrial fibrillation to sinus rhythm, magnesium was compared to a control group which consists of both calcium channel antagonists and amiodarone. Calcium channel antagonists and beta blockers ar...

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  • Iron Reduction and Cardiovascular Outcomes
    Leo R. Zacharski

    Dear Editor,

    The “Heartline Online” description (Heart 2007;93:773-774) of the results of our iron reduction study (JAMA 2007;297:603-610) is only partially correct. Indeed, analysis of the entire cohort showed no difference in outcomes for the primary endpoint, all cause mortality, and the secondary endpoint, combined endpoint of death plus non-fatal myocardial infarction and stroke. However, analysis accord...

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  • Author Response
    Heinz Theres

    Dear Dr. Groves, Dr. Chester, and Editor,

    Thank you for the positive response to our paper on spinal cord stimulation for treatment of patients with refractory angina pectoris.(1)

    At the time when we performed the study and wrote the report, we were not aware of your scientific letter dealing with heart rate variability and spinal cord stimulation.(2) Otherwise we would certainly have discussed it in our paper....

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  • It's good to talk
    Michael R Chester

    Dear Editor,

    In his editorial on ‘Alternative treatments for angina,’ Dr Lanza makes no mention of the value of rehabilitation, especially patient and carer education, in improving quality of life. Given the central role of patient education in [refractory] angina management, this requires comment.

    Damaging misconceptions are common in angina sufferers and their carers, and education is a potent and critica...

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  • Stimulating the memory
    David Groves

    Dear Editor,

    Eddicks and colleagues’ placebo controlled study of spinal cord stimulation in refractory angina is important and interesting work which shows for the first time that patient appreciation of the sensation of spinal cord stimulation is not necessary to achieve clinical benefit.

    The article gives the impression that no previous work had been carried out investigating sub-sensory threshold Spinal...

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  • Papillary Fibroelastoma and Cardiac Conduction Defects
    Suneil K Aggarwal

    Dear Editor,

    I read with interest the case report of a papillary fibroelastoma with heavily calcified bicuspid aortic valve, coronary artery disease and 2nd degree heart block. The authors mention this is the first case of a papillary fibroelastoma presenting with conduction block. While this may be true, it is evident that heavy calcification of a bicuspid aortic valve is a much more common and likely cause of con...

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  • Linear insertion of the AV valves without defect exists and was already described and published
    Catherine Fredouille

    Dear Editor,

    In the article “Can atrioventricular septal defects exist with intact structures?”, the authors seem not to know that a similar case was described on a fetus and published in 2002[1].

    This case was diagnosed through the prenatal ultrasound screening of a supposed partial AVSD which led to the discovery of a Down Syndrome (DS). The parents asked for a termination of pregnancy and a fetal pa...

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