eLetters

208 e-Letters

published between 2005 and 2008

  • Interesting findings in The Hong Kong Heart Failure Study
    Eduardo Rosa

    Dear Editor,

    Patients with heart failure and a normal left ventricular systolic function correspond to almost half of all patients with congestive heart failure(1). However, the great majority of the data presented in the medical literature are related to studies that observe subjects with heart failure followed by systolic dysfunction. It is notable that Yip et al. (2) in their article assess the quality of l...

    Show More
  • Exercise Capacity in Diastolic Heart Failure
    Jackie Taylor

    Dear Editor,

    We read with great interest the article by Yip and colleagues, reporting the results of a randomised controlled trial of diuretics, irbesartan and ramipril in patients with heart failure and normal ejection fraction(1). The authors are to be commended for their contribution to the evidence base for the management of this condition. The PROBE design tested the hypothesis that addition of ramipril or...

    Show More
  • High-dose statin therapy, women and cancer
    Mark R. Goldstein, MD

    Dear Editor,

    We read the interesting secondary analysis of the 4.9-year Treating to New Targets (TNT) study [1] reporting on the effects of aggressive low- density lipoprotein (LDL) cholesterol lowering in women (median age of 63.5 years) with stable coronary heart disease. Based on the reported data, we have serious concerns regarding the large excess in cancer mortality seen among the women randomized to high-d...

    Show More
  • Multilevel analysis for OCT imaging
    Konstantinos Dimopoulos

    Dear Editor,

    Chen et al., present the results of a non-randomised prospective study, in which individual struts in 28 stents implanted in 26 lesions in 24 patients were assessed by OCT. The authors report strut apposition and coverage as binary variables and pool strut-related observations to produce percentages of incompletely apposed/uncovered struts for stents types. It is evident that individual observatio...

    Show More
  • Interesting findings in The Hong Kong Heart Failure Study
    Eduardo M Rosa

    Dear Editor,

    Patients with heart failure and a normal left ventricular systolic function correspond to almost half of all patients with congestive heart failure(1). However, the great majority of the data presented in medical literature are related to studies that observe subjects with heart failure followed by systolic disfunction. It is notable that Yip et al. (2) in your article assess the quality of life and...

    Show More
  • Elevation of BNP in Newborns with Hypertrophic Cardiomyopathy due to Pompe disease
    Wuh-Liang Hwu

    Dear Editor,

    Kaski et al. (1) recently reported that in children with hypertrophic cardiomyopathy (HC) the B-type natriuretic peptide (BNP) level correlated with maximal left ventricular (LV) wall thickness and could be a useful tool in assessing disease severity. In adult patients with HC, circulating plasma BNP has been related to the magnitude of heart failure and can be used to detect HC in patients when symp...

    Show More
  • QRISK - Limitations in Validation?
    Marie Therese Cooney

    Dear Editor,

    We have read with interest the recent article by Hippisley Cox et al on the validation of the new risk estimation function, QRISK. [1] QRISK demonstrated improved discrimination and calibration compared to Framingham in the independent British database, THIN. Previously, we wrote suggesting some methodological limitations in the derivation of the function. [2] Our main concerns were firstly, the use...

    Show More
  • Kamlesh Khunti

    Dear Editor,

    We would like to thank Jaarsma on highlighting an important topic regarding choosing appropriate outcomes in heart failure research. The COACH trial recently found that neither moderate or intensive disease management programmes by a nurse specialising in management of patients with heart failure reduced death or hospitalisation compared to standard treatment. (1) In contrast, our trial evaluated...

    Show More
  • Tissue Doppler Imaging Echocardiography – Technological advancement or retrograde development?
    George Thomas

    Dear Editor,

    I read with great interest the article presenting tissue Doppler techniques as technological advances.[1] The authors conclude with the “limitations” of tissue Doppler stating “There is still a significant variability in TDI (tissue Doppler imaging) derived parameters because of differences in machine characteristics and lack of guidelines for standardization of sample positions and machine setting...

    Show More
  • Bubbles after scuba diving
    Kay Tetzlaff

    Dear Editor,

    With great interest I read the "Images in cardiology" article by Boussuges et al. (1) showing circulating bubbles in the right and the left cavities of a scuba diver's heart after diving. The authors stress the importance of a patent foramen ovale (PFO) as a possible right to left shunting mechanism. However, there are other mechanisms for right to left shunting of intravenous bubbles in scuba diver...

    Show More

Pages