eLetters

151 e-Letters

published between 2009 and 2012

  • Overnight dehydration increases the risk of a morning infarct
    Simon N. Thornton

    Dear Sir, It was with great interest that I read the recent article by A. Suarez- Barrientos and colleagues (1). However, I think there is one very important aspect left out of this very good clinical investigation and that is blood volume. One of the principal problems of heart pumping is having enough blood volume to do this with. If there is insufficient volume then the heart has to alter its rate of contraction, which...

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  • Raison d'etre of Right Ventricle
    Tomoaki Murakami

    To the editor: I read with great interest the report by Dr. Todiere and colleagues1) discussed the right ventricular hypertrophy in patients with systemic hypertension. Although they reported that there was no difference in systolic pulmonary artery pressure between hypertensive patients with and without left ventricular hypertrophy, Lam and colleagues2) previously reported the age-associated elevation of pulmonary arter...

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  • Every physician should read this article
    Gauranga C. Dhar

    In light of recent clinical trials, number of guidelines about the drug treatment in the management of hypertension has amended their strategies. Among many of those, use of diuretics hopefully has been placed at the highest rank. The concept of using a diuretic, an "innocent" agent as the initial drug in the management of hypertension has changed radically e.g. went to as a "third drug" for its number of biochemical and...

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  • Controversies With On-Time 2
    Gen-Min Lin

    To the Editor: We appreciate the work by Hermanides et al, which reported that routine prehospital treatment with high-dose tirofiban (HDT) significantly reduced the use of blinded bail-out study medication (20% vs.29%). The need for bail-out therapy was associated with a less favourable outcome (major adverse cardiac events (MACE) at 30 days 12.2% vs 5.6%). This analysis suggests that routine pretreatment is superior to...

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  • ECG and Chagas' Disease Treatment
    Leonardo Gilardi

    Dear Editor,

    In the excellent paper by Strauss et al,[1] the ECG utility as a screening tool for risk stratification for Chagas' disease is highlighted. ECG is widely available and inexpensive and may be properly interpreted by primary care and clinical physicians.

    It should be added that trypanocide treatment in chronic chagasic adults is becoming a standard of care.[2] Although drugs for treatment of...

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  • Vascular access for primary PCI
    Karim Ratib

    We read with great interest the recent article by Patterson and Foale relating to access site selection for cardiac procedures(1). The authors discuss a series of published trials comparing the use of radial and femoral access sites, and conclude that there is not sufficient evidence to justify a shift from femoral to radial access for most cardiac procedures.

    The radial artery access site was introduced into c...

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  • Transradial primary PCI: this is the time for awareness.
    Bernardo Cortese

    Letter regarding the article "If the radial artery is the new standard of care in primary percutaneous coronary intervention, why is most intervention done by the femoral approach?"

    Because things take some time to change, but we're on the right lane. I must disagree however with the conclusions of this recently published point of view, where T Patterson and RA Foale comment on the performance of trans-radial pr...

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  • Ventilation manoeuvres facilitate MitraClip placement
    N. Patrick Mayr
    To the Editor. It was with great interest that we read the article by Borgia et al. [1] on their experience with an Adenosine-induced asystole to facilitate the grasping of the mitral valve leaflets during a MitraClip procedure. We would like to comment on our experience with an Adenosine-induced asystole and describe an alternative method using ventilation manoeuvres to ease the grasping of the mitral valve leaflets. Borgia et al...
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  • Why NT-proBNP should be less elevated in patients with short onset of atrial fibrillation and/or atrial thrombus?
    Christophe Meune

    We read with great interest the study of Deftereos et al (1) about 86 patients with atrial fibrillation (AF). Half of their population had NT- proBNP level (maximum level within 12 hours) below the cut-off value and half had NT-proBNP level above the cut-off value. In addition, they observed higher rates of atrial thrombus (AT) in the group with reduced NT -proBNP concentration. As stated, this is a proof of concept study a...

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  • CIRCADIAN VARIATIONS AND MELATONIN IN THE ACUTE MYOCARDIAL INFARCTION: STILL A FORGOTTEN EXTRACARDIAC FACTOR.
    Alberto Dominguez-Rodriguez

    To the Editor:

    We read with great interest the article by Su?rez-Barrientos et al (1) regarding circadian oscillations on infarct size. Although the article is both exhaustive and clinically relevant, we felt that the authors failed in the recognition of the potential value of melatonin in the association between cardiovascular events and circadian variation.

    Synchrony between external and internal circ...

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