eLetters

215 e-Letters

published between 2004 and 2007

  • Effect of weather conditions on the mortality of heart attacks in Hungary
    Ildikó Kriszbacher

    Dear Editor,

    We read with great interest the very important article by Dilaveris et al about the climate impacts on myocardial infarction deaths in Athens, Greece [1]. Several reports have already proved that the number of deaths related to acute myocardial infarction (AMI) shows a seasonal variation, with a peak in winter, and a lowest number of mortality rates during the months of summer [2,3,4]. The effects o...

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  • Right ventricular reverse remodelling after sildenafil in pulmonary arterial hypertension
    Ze-Zhou Song

    Dear Editor,

    We read with great interest the study by Wolferen et al1, which confirmed that addition of sildenafil reversed right ventricular (RV) dilatation and hypertrophy in pulmonary arterial hypertension (PAH) patients already receiving treatment and that these positive effects on RV structure and function occurred in parallel with improvements in exercise capacity and N-terminal pro-brain natriuretic peptide (NT-...

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  • Continuous wave Doppler based cardiac output in immersion in swimming athletes
    Karsten Knobloch

    Dear Editor,

    I read with great interest the recent report from Schmid and coworkers regarding the hemodynamic changes induced in water, which is of special interest among patients with deteriorated cardiac function. The hypothesis is interesting, however the methods used for cardiac output determination in a swimming pool have to be discussed. Schmid used an inert gas rebreathing method using an infrared photoa...

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  • Acute Coronary Syndrome. A Progression of Pre-Metabolic Syndrome and the Asian Paradox
    Ram B Singh

    Dear Editor,

    We injoyed very much the most interesting study by Teo et al (1). Acute coronary syndromes(ACS) and coronary risk factors; hypertension, hyperlipidemia,obesity and type 2 diabetes have become a major health problem in Asia with economic development,due to interaction of gene and environmental factors.(2) Overswinging,that is an excessive circadian variation in blood pressure (BP) has been associated with...

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  • Don't blame it "all" on Reperfusion
    Hari Dandapantula

    Dear Editor,

    At the out-set, I want to congratulate the authors of the article "The patho-physiology of myocardial reperfusion: a pathologist's perspective" (1)for an outstanding job in summarizing a complex topic in a simplified way.

    However, it was presented as if “reperfusion” is the culprit ("Reperfusion Injury”), even though, an attempt is made to clarify that the injury after reperfusion is happenin...

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  • Noncompaction patients may profit from neurological investigations
    Claudia Stollberger

    Dear Editor,

    With interest we read the article by McMahon et al. about the application of tissue Doppler imaging (TDI) in assessing the prognosis of children with left ventricular hypertrabeculation/noncompaction (LVHT).[1]

    We have, however, several questions and concerns:

    There are only limited experiences in the follow-up of patients with LVHT and the prognosis is largely unknown.[2] The “undul...

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  • Should we keep looking for “new” and slightly different versions of depression screening tools?
    Brett D. Thombs

    Dear Editor,

    Dr. Huffman and colleagues [1] studied 131 post-myocardial infarction (MI) patients (17 with major depressive disorder [MDD]) and reported that two items from the Beck Depression Inventory (BDI) related to sadness and loss of interest formed an effective screening tool for post-MI depression. The sensitivity and specificity results reported by Huffman et al. are, in fact, highly similar to those repo...

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  • Are the risks of amiodarone exagerated?
    Will B Nicolson

    Dear Editor,

    The Committee for the Safety of Medicines has only two entries for amiodarone extravasation injury, yet almost every consultant seems to remember a patient who has had their arm amputated following extravasation of amiodarone. Surely this is a case of the dangers of peripheral amiodarone being exagerated? In periarrest / cardiac arrest situations amiodarone has been given as a peripheral bolus countl...

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  • Weighing up the risks
    Alasdair I Moonie

    Dear Editor,

    Skin necrosis is a recognised complication of amiodarone infusion, but how does it compare with the risks of central venous cannnulation? The risks are considerable (and potentially fatal), especially if performed by inexperienced junior staff, or in units with no Sonosite or other ultrasound device.
    I think, for many patients, it is reasonable to deliver amiodarone via a large perip...

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  • Percutaneous Coronary Intervention without on-site Cardiac Surgery
    Antoon E Weyne

    Dear Editor,

    From April 2002 until now, our hospital performed 1006 percutaneous coronary interventions (PCIs) without surgical backup on-site. Our total case load is now about 1500 coronary angiograms and 375 PCIs per year, and the number of PCIs performed has increased steadily during the period 2002-2006. In order to improve the access to PCI, a firm debate is ongoing in Belgium whether to choose for stand alone...

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