182 e-Letters

published between 2008 and 2011

  • Propafenone contraindicated in the elderly?
    Paolo Alboni

    We thank Drs Kirchhof, Crijns and van Gelder for their interest in our paper (1) referring pill-in-the-pocket treatment of recent-onset atrial fibrillation (AF). The study was interrupted on the recommendation of the data-and safety-monitoring committee because the results suggested that the intravenous administration of flecainide or propafenone does not predict the occurrence of adverse effects after a loading oral dos...

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  • What is the best dose of aspirin in association with P2Y12 antagonists?
    Marco Cattaneo

    In their Viewpoint article, Warner et al hypothesized that the administration of aspirin to patients who are treated with potent antagonists of the platelet P2Y12 receptors might increase cardiovascular risk.1 The authors' hypothesis is based on the observation that P2Y12 antagonists inhibit the platelet production of thromboxane A2 (TxA2) (which would render the use of aspirin superfluous), and on the consideration tha...

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  • Authors reply: Low sex hormones in heart failure
    Gulmisal Guder

    In their recent editorial in this Journal Theodoraki and Bouloux [1] question the cut-off values employed in our article on the association between circulating androgens and mortality risk in heart failure (HF).[2] While we (according to our local Central Hospital Laboratory) defined androgen deficiency by total testosterone values <180 ng/dl for patients >50 years and 260 ng/dl for younger patients, and by free te...

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  • The patient with hypertrophic cardiomyopathy has a family
    Imke Christiaans

    To the editor: With great interest we have read the paper on hypertrophic cardiomyopathy by ten Berg et al.1 As the paper has an educational aim, we would like to address some minor misconceptions that could have major implications.

    Genotyping in HCM to establish a molecular diagnosis in HCM patients can indeed probably not be used to guide prognosis or therapy. However, it has been proven to be a more cost-effe...

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  • Cardiac imaging training in the United Kingdom
    Edward D Nicol


    Cardiac imaging training in the United Kingdom

    It was with interest that we read the featured correspondence from Rajani et al (ref). We entirely agree with their assertion that there is a growing need for multi-modality cardiac imagers and acknowledge their concerns about the lack of structured "in-programme" training opportunities, such as cardiac imaging fellowships, to support this requireme...

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  • Air Pollution, Weather, and ischaemic cerebral and cardiac events: Methodological Considerations
    Ivy Shiue

    It is with great interest to read a recent article of " Evidence of the role of short-term exposure to ozone on ischaemic cerebral and cardiac events: the Dijon Vascular Project (DIVA)" by Henrotin et al.1 They detailed addressed the analysis procedure and considerations and presented findings on the relationship of air pollution and ischaemic cerebral and cardiac events in a large population-based setting. However, a few...

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  • Assessing aortic strain and stiffness: don't forget the physics and engineering
    Bart Bijnens

    There is more and more evidence that the mechanical properties of the aorta, and arterio-ventricular coupling, are of great clinical importance in cardiovascular diseases. Therefore, we have read the manuscript of Vitarelli et. all with great interest [1]. Whereas, given the recent evolution of ultrasound equipment and processing tools, the idea to assess the aorta using velocity and deformation information is interesting,...

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  • CT or MRI for post-procedural aortic stenting?
    Damien P Kenny

    To the Editor: We thank Dr Rosenthal and Bell for their insightful editorial comments 1 relating to our study. 2 There is little doubt that until we have longer follow-up on the incidence of potential adverse events following coarctation stenting, some form of advanced imaging is required and this is endorsed by ongoing large follow-up studies. 3 Although we agree that with specific imaging techniques MRI may provide inf...

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  • Pacemaker-mediated tachycardia
    Sern Lim

    Ullah and Stewart present a case of pacemaker-mediated tachycardia (PMT). There are 2 specific issues that require clarification. Firstly, the authors suggest that this was a pacemaker malfunction. I would contend that the pacemaker was functioning appropriately as programmed (ie: it is the programming of the pacemaker that resulted in the PMT). Hence, programming changes can often prevent, detect and terminate PMT....

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  • Registry study does not inform us abut management of ACS
    Brett Forge
    Chew et al claim that their registry study six month survival benefits associated with clinical guideline recommendations in acute coronary syndromes 1â₁“suggests that invasive management resulting in revascularisation does provide a reduction in mortality, reinforcing clinical trial data that have relied upon composite ischaemic end points that have at times been inconsistent".

    The very best that...

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